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CANTOR New York Preface This monograph is based on a review on polynucleotide structures written for a book series in 1976. For example, from the de- oxyribonucleic acid (DNA) duplex structure, genetic information is stored, accessed, and replicated as a linear nucleotide code. In some cases the availability of texts in active research areas should help stimulate the creation of new courses. These should serve the needs of one semester or one quarter graduate courses in chemistry and biochemistry. A double helix composed of two polynucleotides joined together by hydrogen bonds between complementary bases. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive introductions to their fields. The structure of a polynucleotide is shown.

It is not often easy to persuade such individuals to set time aside to help spread the knowledge they have accumulated. Because a nucleic acid is a polymer of many nucleotide molecules, DNA and RNA molecules are called polynucleotides. Textbooks in these subjects usually have to be written by scientists actually involved in the research which is advancing the field. The most serious needs occur in fields that are rapidly changing. A structure for nucleic acid has already. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. The RCSB PDB also provides a variety of tools and resources.

However, some areas of chemistry, especially many of those taught at the grad­ uate level, suffer from a real lack of up-to-date textbooks. This structure has novel features which are of considerable biological interest. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. Some fields like basic biochemistry, organic reaction mechanisms, and chemical ther­ modynamics are well represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. Nucleic acids are composed of aromatic bases (a purine or. For the two strands of the double helix to fit neatly, a pyrimidine must always be paired with a purine.New textbooks at all levels of chemistry appear with great regularity. In order to understand how DNA and RNA can carry out their functions, lets look at their structures. If these pairings were ever to occur, the structure of DNA would be like a staircase made with stairs of different widths. A nucleic acid sequence is the order of nucleotides within a DNA (GACT) or RNA (GACU) molecule that is determined by a series of letters. The structure, function and reactions of nucleic acids are central to molecular biology and are crucial for the understanding of complex biological processes.